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Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.

Identifieur interne : 002A83 ( Main/Exploration ); précédent : 002A82; suivant : 002A84

Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.

Auteurs : Yan Wang [République populaire de Chine] ; Jiangwei Yan ; Yuling Shi ; Ping Li ; Chuanxuan Liu ; Qingjun Ma ; Ruifu Yang ; Xiaoyi Wang ; Lina Zhu ; Xiao Yang ; Cheng Cao

Source :

RBID : pubmed:19405982

Descripteurs français

English descriptors

Abstract

The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.

DOI: 10.1186/1471-2334-9-51
PubMed: 19405982


Affiliations:


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Le document en format XML

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<term>Genetic Predisposition to Disease</term>
<term>Genotype</term>
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<term>Male</term>
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<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Fréquence d'allèle</term>
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<term>Humains</term>
<term>Jeune adulte</term>
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<div type="abstract" xml:lang="en">The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.</div>
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